It's alluded to in the game's title, borrowed from the myth that features in all three major monotheistic religions in which Abraham comes close to sacrificing his bewildered child, Isaac. While its numerous opaque endings are open to interpretation, there is no way to shy away from its distressing foundational theme. The Binding of Isaac is a game about child abuse, both mythological and semi-autobiographical. An awful childhood gets a surprisingly arcadey revisit in this blistering action roguelike.